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Kızılay G, Ersoy O, Cerkezkayabekir A, Topcu-Tarladacalisir Y. Sitagliptin and fucoidan prevent apoptosis and reducing ER stress in diabetic rat testes. Andrologia.53(3):e13858. doi: 10.1111/and.13858

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Sitagliptin attenuates neuronal apoptosis via inhibiting the endoplasmic reticulum stress after acute spinal cord injury
Role of Endoplasmic Reticulum Stress in The Male Reproductive System
Low-dose lipopolysaccharide inducing continuous and obvious increase in urinary protein in hyperglycemic rats and the underlying mechanism
The Effects of Sargassum horneri Extract and Fucoidan on Tear Hyposecretion and Ocular Surface Injury in Rats with Dry Eye Diseases
Quercetin ameliorates testosterone secretion disorder by inhibiting endoplasmic reticulum stress through the miR-1306-5p/HSD17B7 axis in diabetic rats
Sitagliptin Attenuates the Cognitive Deficits in L-Methionine-Induced Vascular Dementia in Rats
Glucose fluctuation promotes cardiomyocyte apoptosis by triggering endoplasmic reticulum (ER) stress signaling pathway in vivo and in vitro
Linagliptin and Vitamin D3 Synergistically Rescue Testicular Steroidogenesis and Spermatogenesis in Cisplatin-Exposed Rats: The Crosstalk of Endoplasmic Reticulum Stress with NF-kappa B/iNOS Activation
Sitagliptin Reduces Endothelial Dysfunction and Apoptosis Induced by High-Fat Diet and Palmitate in Thoracic Aortas and Endothelial Cells via ROS-ER Stress-CHOP Pathway Cao, QQ; Xu, DM; (...); Lu, YX Aug 31 2021 | FRONTIERS IN PHARMACOLOGY 12
Effects and Mechanism of Zishen Jiangtang Pill on Diabetic Osteoporosis Rats Based on Proteomic Analysis Chu, SF; Liu, DL; (...); Li, HL Sep 25 2021 | EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 2021

The effects of epidermal growth factor on early burn-wound progression in rats. Dermatol Ther. e13196. doi: 10.1111/dth.

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The effect of Tarantula cubensis D6 on zone of stasis in a rat burn model
Keratinized tissue augmentation using collagen-based soft tissue substitute with/without epidermal growth factor on buccally positioned implants: a pilot preclinical study
Paediatric Partial-Thickness Burn Therapy: A Meta-Analysis and Systematic Review of Randomised Controlled Trials
Modeling Burn Progression Using Comb Burns: The Impact of Thermal Contact Duration on Model Outcomes Smith, RD; Carney, BC; (...); Moffatt, LT Apr 2021 | JOURNAL OF SURGICAL RESEARCH 260 , pp.155-162
Curcumin/Fe-SiO2 nano composites with multi-synergistic effects for scar inhibition and hair follicle regeneration during burn wound healing Zhang, ZWB; Zhang, Y; (...); Chang, J Jun 2021 | APPLIED MATERIALS TODAY 23
Growth Factors, Reactive Oxygen Species, and Metformin-Promoters of the Wound Healing Process in Burns? Miricescu, D; Badoiu, SC; (...); Greabu, M Sep 2021 | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 (17)

The effect of platelet-rich plasma in inactive form on the burn zone of stasis in rats. J Plast Surg Hand Surg. 53(5): 301-308

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L-Carnitine counteracts prepubertal exposure to cisplatin-induced impaired sperm in adult rats by preventing germ cell apoptosis

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In vivo Gonadoprotective Effects of Myricetin on CisplatinInduced Testicular Damage via Suppression of TLR4/NF-κB Inflammation Pathway and Heat-Shock Response
Zinc oxide nanoparticles attenuate prepubertal exposure to cisplatin-induced testicular toxicity and spermatogenesis impairment in rats
PROTECTIVE EFFECTS OF L-CARNITINE ON REPRODUCTIVE CAPACITY IN RATS WITH DIABETES Li, XF; Shi, ZD; (...); Liu, HY Feb 2021 | JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 72 (1) , pp.111-117
Tranilast abrogates cisplatin-induced testicular and epididymal injuries: An insight into its modulatory impact on apoptosis/proliferation Makled, MN and Said, E Aug 2021 | May 2021 (Early Access) | JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 35 (8)
L-carnitine extenuates endocrine disruption, inflammatory burst and oxidative stress in carbendazim-challenged male rats via upregulation of testicular StAR and FABP9, and downregulation of P38-MAPK pathways Salem, MA; Ismail, RS; (...); El-Khatib, ASN Jun 15 2021 | TOXICOLOGY 457
Vitamin B12 suppresses GADD153, prevents apoptosis and regulates the testicular function in methotrexate treated rat testis Karabulut, D; Ozturk, E; (...); Yakan, B Aug 2021 (Early Access) | BIOTECHNIC & HISTOCHEMISTRY
Effects of chemotherapeutic agents on male germ cells and possible ameliorating impact of antioxidants Ghafouri-Fard, S; Shoorei, H; (...); Ayatollahi, SA Oct 2021 | BIOMEDICINE & PHARMACOTHERAPY 142
Natural products against cisplatin-induced male reproductive toxicity: A comprehensive review Rahimi, A; Asadi, F; (...); Memariani, Z Nov 2021 (Early Access) | JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
The protective role of L-carnitine on spermatogenesis after cisplatin treatment during prepubertal period in rats: A pathophysiological study Aboul-Naga, AM; Hamam, ET; (...); Shokeir, AA Oct 1 2020 | LIFE SCIENCES 258
Resveratrol treatment reduces apoptosis and morphological alterations in cisplatin induced testis damage Ozyilmaz Yay, N; Sener, G and Ercan, F 2019 | JOURNAL OF RESEARCH IN PHARMACY 23 (4) , pp.621-631
Naringenin palliates cisplatin and doxorubicin gonadal toxicity in male rats Fouad, AA; Refaie, MMM and Abdelghany, MI Jan 2 2019 | TOXICOLOGY MECHANISMS AND METHODS 29 (1) , pp.67-73
Effects of L-Carnitine on the sperm parameters disorders, apoptosis of spermatogenic cells and testis histopathology in diabetic Rats Mardanshahi, T; Rezaei, N; (...); Mohammadi, H May 2019 | INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE 17 (5) , pp.325-336

M. M. SAPMAZ, Y. T. TOPÇU, I. Ö. KURT, B. KARAÖZ, S. A. ÜNSAL, A morphological study of uterine alterations in mice due to exposure to cadmium, Biotechnic and Histochemistry, 2017 (Şubat 2017)

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Procyanidin B2 alleviates uterine toxicity induced by cadmium exposure in rats: The effect of oxidative stress, inflammation, and gut microbiota
Influence of Lactobacillus plantarum administration on some serum/tissue (uterus) antioxidant and cytokine levels in female rats exposed to cadmium (Cd)
An Assessment of Metallothionein-Cadmium Binding in Rat Uterus after Subchronic Exposure Using a Long-Term Observation Model (Şubat 2022)
Subacute cadmium exposure disrupts the hypothalamic-pituitary-gonadal axis, leading to polycystic ovarian syndrome and premature ovarian failure features in female rats da Costa, CS; Oliveira, TF; (...); Graceli, JB Jan 15 2021 | ENVIRONMENTAL POLLUTION 269
Cadmium and immunologically-mediated homeostasis of anatomical barrier tissues Aleksandrov, AP; Mirkov, I; (...); Kataranovski, M Feb 1 2021 | TOXICOLOGY LETTERS 337 , pp.38-45
Effects of Endocrine-Disrupting Chemicals on Endometrial Receptivity and Embryo Implantation: A Systematic Review of 34 Mouse Model Studies Caserta, D; Costanzi, F; (...); Ruscito, I Jul 2021 | INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 18 (13)
Immunomodulation by heavy metals as a contributing factor to inflammatory diseases and autoimmune reactions: Cadmium as an example Aleksandrov, AP; Mirkov, I; (...); Kataranovski, M Dec 2021 | IMMUNOLOGY LETTERS 240 , pp.106-122

Topcu-Tarladacalisir Y, Sapmaz-Metin M, Karaca T. Curcumin counteracts cisplatin-induced nephrotoxicity by preventing renal tubular cell apoptosis. Ren Fail. 19:1-8, (2016).

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The modulation of sirtuins by natural compounds in the management of cisplatin-induced nephrotoxicity
Curcumin supplementation prevents cisplatin-induced nephrotoxicity: a randomized, double-blinded, and placebo-controlled trial
Sinapic Acid Attenuated Cisplatin-Induced Cardiotoxicity by Inhibiting Oxidative Stress and İnflammation with GPX4-Mediated NF-kB Modulation
Involvement of the inhibition of mitochondrial apoptotic, p53, NF-κB pathways and the activation of Nrf2/HO-1 pathway in the protective effects of curcumin against copper sulfate-induced nephrotoxicity in mice
Potential therapeutic effects of Chinese meteria medica in mitigating drug-induced acute kidney injury
Novel insights into the augmented effect of curcumin and liraglutide in ameliorating cisplatin-induced nephrotoxicity in rats: Effects on oxidative stress, inflammation, apoptosis and pyroptosis via GSK-3β
Curcumin Mitigates Malathion-Induced Renal Injury: Suppression of Apoptosis and Modulation of NF-κβ/TNF-α and Nrf2, and HO-1 Signaling
Wnt/?-catenin inhibitor pyrivinium attenuates cisplatin-induced acute kidney injury by possibly reducing platinum uptake and accumulation mediated by reduced organic cation transporter-2 expressions
Clonidine ameliorates cisplatin-induced nephrotoxicity: impact on OCT2 and p38 MAPK pathway
Curcumin enhances p-cresyl sulfate-induced cytotoxic effects on renal tubular cells
Advances in pharmacotherapy for acute kidney injury
Nephroprotective potential of Sharbat-e-Bazoori Motadil (sugar-free) in HEK-293 cells and Wistar rats against cisplatin induced nephrotoxicity
An overview of nephroprotective plants in the Indian traditional system of Medicine
Prediction of the mechanisms of action of Zhibai Dihaung Granule in cisplatin-induced acute kidney injury: A network pharmacology study and experimental validation
Pro-Inflammatory Signalling PRRopels Cisplatin-Induced Toxicity
MicroRNAs Involved in Intrinsic Apoptotic Pathway during Cisplatin-Induced Nephrotoxicity: Potential Use of Natural Products against DDP-Induced Apoptosis
Cisplatin for cancer therapy and overcoming chemoresistance
Relationship with nephrotoxicity of Abemaciclib in rats: Protective effect of Curcumin
Cisplatin chemotherapy and renal function Zhang, J; Ye, ZW; (...); Townsend, DM 2021 | ADVANCES IN CANCER RESEARCH, VOL 152 152 , pp.305-327
Natural products: potential treatments for cisplatin-induced nephrotoxicity Fang, CY; Lou, DY; (...); Weng, QJ Dec 2021 | Mar 2021 (Early Access) | ACTA PHARMACOLOGICA SINICA 42 (12) , pp.1951-1969
Protective Effect of Curcumin against Sodium Salicylate-Induced Oxidative Kidney Damage, Nuclear Factor-Kappa Dysregulation, and Apoptotic Consequences in Rats Abd-Elhakim, YM; Moselhy, AAA; (...); El Deib, MM Jun 2021 | ANTIOXIDANTS 10 (6)
Regression Modeling of the Antioxidant-to-Nephroprotective Relation Shows the Pivotal Role of Oxidative Stress in Cisplatin Nephrotoxicity Casanova, AG; Harvat, M; (...); Martin-Guerrero, JD Sep 2021 | ANTIOXIDANTS 10 (9)
Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects Abadi, AJ; Mirzaei, S; (...); Sethi, G Oct 2021 (Early Access) | PHYTOTHERAPY RESEARCH
Mitigation of IL beta-1, IL beta-6, TNF-alpha, and markers of apoptosis by ursolic acid against cisplatin-induced oxidative stress and nephrotoxicity in rats Tripathi, P and Alshahrani, S Dec 2021 | HUMAN & EXPERIMENTAL TOXICOLOGY 40 (12_SUPPL) , pp.S397-S405
Potassium bromate-induced kidney damage in rats and the effect of gum acacia thereon
Renoprotective Effect of Platelet-Rich Plasma on Cisplatin-Induced Nephrotoxicity in Rats
Prediction of Drug-Induced Nephrotoxicity with a Hydroxyl Radical and Caspase Light-Up Dual-Signal Nanoprobe
Cisplatin-induced oxidative stress stimulates renal Fas ligand shedding
Protective effects of amifostine, curcumin, and melatonin against cisplatin-induced acute kidney injury
Perindopril regulates the inflammatory mediators, NF-B/TNF-/IL-6, and apoptosis in cisplatin-induced renal dysfunction
Nephroprotective Effects of Benzyl Isothiocyanate and Resveratrol Against Cisplatin-Induced Oxidative Stress and Inflammation
The effect of sildenafil on rats with adenine-Induced chronic kidney disease
He-Wei granules (HWKL) combat cisplatin-induced nephrotoxicity and myelosuppression in rats by inhibiting oxidative stress, inflammatory cytokines and apoptosis (Şubat 2017)
The Protective Effect of Naringenin-Oxime on Cisplatin-Induced Toxicity in Rats (Şubat 2017)
Curcumin prevents cisplatin-induced renal alterations in mitochondrial bioenergetics and dynamic (Ocak 2017)
Novel Therapies for Acute Kidney Injury (Ocak 2017)

Bayram S, Kizilay G, Topcu-Tarladacalisir Y. Evaluation of Fas/FasL Signaling Pathway in Diabetic Rat Testes. Biotechnic & Histochemistry. (2016).

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Abnormalities in sex hormones and sexual dysfunction in males with diabetes mellitus: A mechanistic insight
Icariin improves testicular dysfunction via enhancing proliferation and inhibiting mitochondria-dependent apoptosis pathway in high-fat diet and streptozotocin-induced diabetic rats He, WG; Liu, HQ; (...); Lei, XC Nov 9 2021 | REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY 19 (1)
Effects of saturated palmitic acid and omega-3 polyunsaturated fatty acids on Sertoli cell apoptosis
he contribution of p53 and Y chromosome long arm genes to regulation of apoptosis in mouse testis
A morphological study of uterine alterations in mice due to exposure to cadmium (Mart 2017)
Diabetes associated with male reproductive system damages: Onset of presentation, pathophysiological mechanisms and drug intervention (Şubat 2017)
High glucose levels affect spermatogenesis: an in vitro approach (Şubat 2017)
Emodin alleviates severe acute pancreatitis-associated acute lung injury by decreasing pre-B-cell colony-enhancing factor expression and promoting polymorphonuclear neutrophil apoptosis (Şubat 2017)

Y. Topcu-Tarladacalisir, T. Tarladacalisir, M. Sapmaz-Metin, A. Karamustafaoglu, Y.H. Uz, M. Akpolat, A. Cerkezkayabekir, F.N. Turan, “N-acetylcysteine counteracts oxidative stress and protects alveolar epithelial cells from lung contusion-induced apoptosis in rats with blunt chest trauma”, J Mol Histol, 45(4), 2014; 463-471

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Ayvaz S, Aksu B, Karaca T, Cemek M, Topcu Tarladacalisir Y, Ayaz A, Sapmaz Metin M, Basaran UN, Tor Ayvaz A, Aksu F, Pul M. Effects of methylene blue in acute lung injury induced by blunt chest trauma. Hippokratia. 18(1), (2014), 50-56

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Bozdemir Donmez Y, Kizilay G, Topcu-Tarladacalisir Y. MAPK immunreactivity in streptozotocin-induced diabetic rat testis. Acta Cir Bras. 29(10), (2014), 644-50

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M. Sapmaz-Metin, Y. Topcu-Tarladacalisir, Y.H. Uz, M. Inan, İ. Kurt Omurlu, A. Cerkezkayabekir, G. Kızılay, M. Akpolat, “Vitamin E modulates apoptosis and c-jun N-terminal kinase activation in ovarian torsion-detorsion injury”, Exp Mol Pathol, 95(2), 213-219, 2013

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Biochemical and immunohistochemical examination of the effects of ephedrine in rat ovary tissue
Therapeutic potential of vitamin D against bisphenol A-induced spleen injury in Swiss albino mice
Trends in metabolic dysfunction in polycystic ovary syndrome: a bibliometric analysis
Effect of trimetazidine against ovarian ischemia/reperfusion injury in rat model: A new pathway: JAK2/STAT3
Evaluation of the protective effects of gossypin for ischemia/reperfusion injury in ovary tissue
The relationship between vitamin E level and premature ovarian insufficiency Ma, LJ; Chen, GL; (...); Zhou, JH Apr 2021 | Jan 2021 (Early Access) | JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH 47 (4) , pp.1481-1486
The Protective Effect of Cx43 Protein-Mediated Phosphocreatine on Myocardial Ischemia/Reperfusion Injury Wang, CX; Guo, JJ; (...); Yan, GL Jan 23 2021 | CARDIOLOGY RESEARCH AND PRACTICE 2021
Evaluation of the protective effects of gossypin for ischemia/reperfusion injury in ovary tissue Dincer, B; Cinar, I; (...); Toktay, E Dec 2021 (Early Access) | JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
Protective effects of vitamin D on ischemia-reperfusion injury of the ovary in a rat model
Immunoexpression of vascular endothelial growth factor and B-cell lymphoma 2 in the uterine tissue of rats treated with melatonin in the estrus phase
Protective effect of hydrogen rich saline solution on experimental ovarian ischemia reperfusion model in rats (Şubat 2017)
Antioxidant and antiapoptotic effects of erdosteine in a rat model of ovarian ischemia-reperfusion injury (Ocak 2017)
Adnexal torsion in adolescents: update and review of the literature C Spinelli, J Piscioneri, S Strambi - Current Opinion in Obstetrics …, 2015
Germ Cell Apoptosis: Clinical Implications I Sukhotnik, A Rofe - Andrology-Open Access, 2015

İnan M, Uz YH, Kızılay G, Topcu-Tarladacalisir Y, Sapmaz-Metin M, Akpolat M, Aydoğdu N. Protective effect of sildenafil on liver injury induced by intestinal ischemia/refusion. Journal of Pediatric Surgery 48(8), 1707-1715, 2013

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A new insight into the hepatoprotective effect of sildenafil: The role of H2S
Mechanism Involved in Acute Liver Injury Induced by Intestinal Ischemia-Reperfusion
Albendazole ameliorates inflammatory response in a rat model of acute mesenteric ischemia reperfusion injury
The Nrf2 Signaling in Retinal Ganglion Cells under Oxidative Stress in Ocular Neurodegenerative Diseases
Olprinone protects the liver from ischemia-reperfusion injury through oxidative stress prevention and protein kinase Akt activation
Protective effect of glutamine on the main and adjacent organs damaged by ischemia-reperfusion in rats (Şubat 2017)
Mesenchymal stem cells increase antioxidant capacity in intestinal ischemia/reperfusion damage (Şubat 2017)
Protective Effect of Mesna on Intestinal Ischemia- reperfusion Injury by Nitric Oxide and Arginase in an Experimental Rat Model (Ocak 2017)
Effect of combined anti-inflammatory and antioxidant therapy on ischemia-reperfusion injury in rat ovary: an experimental study
Mechanisms of Enhanced Vasoconstriction in the Mouse Model of Atherosclerosis: the Beneficial Effects of Sildenafil MA Leal, CM Balarini, AT Dias… - Current …, 2015
Sildenafil improves vascular endothelial structure and function in renovascular hypertension BM Fahning, AT Dias, JP Oliveira… - Current …, 2015
Protective effect of exercise and sildenafil on acute stress and cognitive function D Ozbeyli, AG Gokalp, T Koral, OY Ocal, B Dogan… - Physiology & …, 2015
Does sildenafil have protective effects against ovarian ischemia-reperfusion injury in rats? A Incebiyik, A Seker, H Camuzcuoglu… - Archives of gynecology …, 2015
Sildenafil ameliorates biomarkers of genotoxicity in an experimental model of spontaneous atherosclerosis

Akpolat M, Gulle K, Topcu-Tarladacalisir Y, Safi Oz Z, Bakkal BH, Arasli M, Ozel Turkcu U. Protection by L-carnitine against radiation-induced ileal mucosal injury in the rat: pattern of oxidative stress, apoptosis and cytokines. Int J Radiat Biol 89(9), 732-740,2013

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The Cytokines-Directed Roles of Spirulina for Radioprotection of Lacrimal Gland
Variable Dose Rates in Realistic Radiation Exposures: Effects on Small Molecule Markers of Ionizing Radiation in the Murine Model
The Protective Effects ofl-Carnitine and Zinc Oxide Nanoparticles Against Diabetic Injury on Sex Steroid Hormones Levels, Oxidative Stress, and Ovarian Histopathological Changes in Rat Majidi, FZ; Rezaei, N; (...); Abediankenari, S Mar 2021 | Sep 2020 (Early Access) | REPRODUCTIVE SCIENCES 28 (3) , pp.888-896
Immunological modulation of the Th1/Th2 shift by ionizing radiation in tumors (Review) Li, JL; Zeng, ZH; (...); Xie, CH Jul 2021 | INTERNATIONAL JOURNAL OF ONCOLOGY 59 (1)
Protective Effects of Quercetin on Intestinal Damage Caused by Ionizing Radiation
L-carnitine preserves cardiac function by activating p38 MAPK/Nrf2 signalling in hearts exposed to irradiation (Şubat 2017)
Novel concepts in radiation-induced cardiovascular disease
Effects of L-carnitine and/or maize distillers dried grains with solubles in diets of gestating and lactating sows on the intestinal barrier functions of their offspring
Acetyl-L-Carnitine protects HEI-OC1 auditory cells from radiation and cisplatin induced toxicity By: Altun, Zekiye; Pamukoglu, Ayca; Olgun, Yuksel; et al. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE Acetyl-L-Carnitine protects HEI-OC1 auditory cells from radiation and cisplatin induced toxicity Volume: 9 Issue: 7 Pages: 13605-13614 Published: 2016
The protective effects of apocynin on ionizing radiation-induced intestinal damage in rats YF Cagin, H Parlakpinar, A Polat, N Vardi… - Drug development …, 2015
Reduced levels of plasma polyunsaturated fatty acids and serum carnitine in autistic children: relation to gastrointestinal manifestations GA Mostafa, LY Al-Ayadhi - Behavioral and Brain Functions, 2015

Topcu-Tarladacalisir Y, Akpolat M, Uz YH, Kizilay G, Sapmaz Metin M, Cerkezkayabekir A, Kurt Omurlu İ. Effects of Curcumin on Apoptosis and Oxidoinflammatory Regulation in Rat Model of Acetic Acid-induced Colitis: Role of JNK and p38 MAPK. J Med Food, 16(4); 1-10, 2013

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A biomimetic study of aliphatic and aromatic dicarboxylic acids engineered β-CD targeted for intestinal maladies
Eicosapentaenoic acid mitigates ulcerative colitis-induced by acetic acid through modulation of NF-κB and TGF-β/EGFR signaling pathways
Impact of curcumin on p38 MAPK: therapeutic implications
Oxidative stress, hormones, and effects of natural antioxidants on intestinal inflammation in inflammatory bowel disease
Curcumin Alleviates Dextran Sulfate Sodium-Induced Colitis in Mice Through Regulating Gut Microbiota
Efficacy of oral consumption of curcumin/Curcuma longa for symptom improvement in inflammatory bowel disease: A systematic review of animal models and a meta-analysis of randomized clinical trials
Natural Products Modulate Cell Apoptosis: A Promising Way for the Treatment of Ulcerative Colitis
Protective effects of nanomicelle curcumin on the phosphine-induced oxidative stress and apoptosis in human liver HepG2 cells
A Pharmacoinformatics Analysis of Artemisinin Targets and de novo Design of Hits for Treating Ulcerative Colitis
Review of the Effects and Mechanism of Curcumin in the Treatment of Inflammatory Bowel Disease
Curcumin activates Nrf2/HO-1 signaling to relieve diabetic cardiomyopathy injury by reducing ROS in vitro and in vivo
Curcumin and inflammatory bowel diseases: From in vitro studies to clinical trials Fallahi, F; Borran, S; (...); Mirzaei, H Feb 2021 | MOLECULAR IMMUNOLOGY 130 , pp.20-30
Antioxidant Therapy in Inflammatory Bowel Diseases Dziabowska-Grabias, K; Sztanke, M; (...); Sztanke, K Mar 2021 | ANTIOXIDANTS 10 (3)
Curcumin and Its Modified Formulations on Inflammatory Bowel Disease (IBD): The Story So Far and Future Outlook Karthikeyan, A; Young, KN; (...); Min, T Apr 2021 | PHARMACEUTICS 13 (4)
Dietary Curcumin Alleviated Acute Ileum Damage of Ducks (Anas platyrhynchos) Induced by AFB1 through Regulating Nrf2-ARE and NF-kappa B Signaling Pathways Jin, SJ; Yang, H; (...); Feng, XJ Jun 2021 | FOODS 10 (6)
The Clinical Spectrum of Inflammatory Bowel Disease Associated With Specific Genetic Syndromes: Two Novel Pediatric Cases and a Systematic Review Gatti, S; Gelzoni, G; (...); Catassi, C Oct 26 2021 | FRONTIERS IN PEDIATRICS 9
Exploration of the Potential Mechanisms of Wumei Pill for the Treatment of Ulcerative Colitis by Network Pharmacology Huang, JK; Zheng, YJ; (...); Tang, XD Dec 21 2021 | GASTROENTEROLOGY RESEARCH AND PRACTICE 2021
Curcumin, A Polyphenolic Curcuminoid With Its Protective Effects and Molecular Mechanisms in Diabetes and Diabetic Cardiomyopathy
Octacosanol Attenuates Inflammation in Both RAW264.7 Macrophages and a Mouse Model of Colitis (Şubat 2017)
Diet as a Trigger or Therapy for Inflammatory Bowel Diseases (Şubat 2017)
Pathomechanisms of Oxidative Stress in Inflammatory Bowel Disease and Potential Antioxidant Therapies (Şubat 2017)
Claudin-3 and occludin content in the glands of colonic mucosa devoid from fecal stream submitted to topical intervention with oil extract of Curcuma longa (Şubat 2017)
Oxidative Stress and Carbonyl Lesions in Ulcerative Colitis and Associated Colorectal Cancer
In vivo effects of curcumin on the paraoxonase, carbonic anhydrase, glucose-6-phosphate dehydrogenase and beta-glucosidase enzyme activities in dextran sulphate sodium-induced ulcerative colitis mice
Effect of turmeric on colon histology, body weight, ulcer, IL-23, MPO and glutathione in acetic-acid-induced inflammatory bowel disease in rats
Curcumin and Health
Curcumin as a therapeutic agent in the chemoprevention of inflammatory bowel disease
Antioxidant therapy for treatment of inflammatory bowel disease: Does it work? FA Moura, KQ de Andrade, JCF dos Santos… - Redox biology, 2015
Curcumin, Inflammation, and Chronic Diseases: How Are They Linked? Y He, Y Yue, X Zheng, K Zhang, S Chen, Z Du - Molecules, 2015
A review of the efficacy of dietary polyphenols in experimental models of inflammatory bowel diseases DA Martin, BW Bolling - Food & function, 2015
Oxidative Stress and Carbonyl Lesions in Ulcerative Colitis and Associated Colorectal Cancer Z Wang, S Li, Y Cao, X Tian, R Zeng… - Oxidative Medicine
The beneficial role of curcumin on inflammation, diabetes and neurodegenerative disease: A recent update S Ghosh, S Banerjee, PC Sil - Food and Chemical Toxicology,
Protective effect of curcumin against heavy metals-induced liver damage
Curcumin, a component of golden spice: From bedside to bench and back

Role of Amifostine on Acute and Late Radiation Nephrotoxicity: A Histopathological Study By: Kanter, Mehmet; Topcu-Tarladacalisir, Yeter; Uzal, Cem IN VIVO M. Kanter, Y. Topcu-Tarladacalisir, C. Uzal, “Role of amifostine on acute and late radiation nephrotoxicity: A histopathological study”, In Vivo, 25(1), 77-86, (2011).

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Proliferative and apoptotic evaluations of renal preventive effects of coenzyme Q10 in radioiodine-131 induced renal damage
Kidney cell DNA damage caused by combined exposure to volatile anaesthetics and 1 Gy or 2 Gy radiotherapy dose in vivo
Radiomodulatory effects of Aloe vera on hepatic and renal tissues of X-ray irradiated mice
Apoptosis and cell proliferation in short-term and long-term effects of radioiodine-131-induced kidney damage: an experimental and immunohistochemical study
Effect of Coenzyme Q10 on Radiation Nephropathy in Rats (Şubat 2017)
The effect of amifostine on differentiation of the human megakaryoblastic Dami cell line
Radiation-induced acute kidney toxicity: Protective effect of L-carnitine versus amifostine

Akpolat M, Kanter M, Topcu-Tarladacalisir Y, Aydogdu N. Protective effect of flaxseed oil on renal injury in hyperlipidemic rats. Phytother Res. 25(6): 796-802, 2011.

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Treatment of Lupus Nephritis from Iranian Traditional Medicine and Modern Medicine Points of View: A Comparative Study Vahedi-Mazdabadi, Y and Saeedi, M Nov 9 2021 | EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 2021
Flaxseed supplementation on glucose control and insulin sensitivity: a systematic review and meta-analysis of 25 randomized, placebo-controlled trials
The potential protective influence of flaxseed oil against renal toxicity induced by thioacetamide in rats
Natural antioxidants in the treatment and prevention of diabetic nephropathy; a potential approach that warrants clinical trials (Ocak 2017)
Flaxseed Supplementation in Metabolic Syndrome Management: A Pilot Randomized, Open-labeled, Controlled Study
2. Characterization of constituents, quality and stability of pomegranate seed oil (Punica granatum L.)
Maternal use of a diet rich omega‐3 from flaxseed improves aortic remodeling but not the biochemical parameters of female offspring of diabetic rats GC Vicente, AM Correia‐Santos… - European Journal of …, 2015

Akpolat M, Topcu-Tarladacalisir Y, Dokmeci D, Turan FN, Uzal MC. Protective effects of ibuprofen and L-carnitine against whole body gamma irradiation-induced duodenal mucosal injury. Balkan Med J. 28: 80-85, 2011.

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Kanter M, Topcu-Tarladacalisir Y, Parlar S. Antiapoptotic effect of L-carnitine on testicular irradiation in rats. J Mol Hist. 41(2-3): 121-128, 2010.

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Effects of X-ray application on infertility in new-born rats
The Role of Dietary Nutrients in Male Infertility: A Review
Zinc oxide nanoparticles attenuate prepubertal exposure to cisplatin-induced testicular toxicity and spermatogenesis impairment in rats
Levels of L-carnitine in human seminal plasma are associated with sperm fatty acid composition
Protective effects of chlorogenic acid against ionizing radiation-induced testicular toxicity
PROTECTIVE EFFECTS OF L-CARNITINE ON REPRODUCTIVE CAPACITY IN RATS WITH DIABETES Li, XF; Shi, ZD; (...); Liu, HY Feb 2021 | JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 72 (1) , pp.111-117
The effects of L-carnitine on renal function and gene expression of caspase-9 and Bcl-2 in monosodium glutamate-induced rats Koohpeyma, F; Siri, M; (...); Dastghaib, S May 2 2021 | BMC NEPHROLOGY 22 (1)
Comparison of 3-and 6-Month Outcomes of Combined Oral L-Carnitine Fumarate and Acetyl-L-Carnitine Therapy, Included in an Antioxidant Formulation, in Patients with Idiopathic Infertility Szymanski, M; Wandtke, T; (...); Domaracki, P Sep 2021 | AMERICAN JOURNAL OF MENS HEALTH 15 (5)
Carnitine partially improves oxidative stress, acrosome integrity, and reproductive competence in doxorubicin-treated rats
Effects of telmisartan and losartan on irradiated testes
Effects of l-Carnitine on the Follicle-Stimulating Hormone, Luteinizing Hormone, Testosterone, and Testicular Tissue Oxidative Stress Levels in Streptozotocin-Induced Diabetic Rats
Potential Radioprotective Effect of AT(1) Receptor Antagonists Against Morphological and Ultrastructural Changes in the Testes Induced by Ionizing Radiation (Mart 2017)
Carnitine and adiponectin levels in breast cancer after radiotherapy (Mart 2017)
Evaluation of serum level of Osteocalcin hormone in male infertility (Şubat 2017)
L-carnitine preserves cardiac function by activating p38 MAPK/Nrf2 signalling in hearts exposed to irradiation (Şubat 2017)
Enhancement of X-ray Induced Apoptosis by Mobile Phone-Like Radio-Frequency Electromagnetic Fields in Mouse Spermatocyte-Derived Cells (Şubat 2017)
Carnitine-mediated antioxidant enzyme activity and Bcl2 expression involves peroxisome proliferator-activated receptor-gamma coactivator-1 alpha in mouse testis (Şubat 2017)
Beneficial effects of aminoguanidine on radiotherapy-induced kidney and testis injury
The role of carnitine in male infertility
The protective effect of L-carnitine in cyclophosphamide-induced germ cell apoptosis B ZHU, Y ZHENG, Y ZHANG, Y CAO, L ZHANG, X LI...
L-Carnitine protects against testicular dysfunction caused by gamma irradiation in mice
Extremely low-frequency magnetic fields can impair spermatogenesis recovery after reversible testicular damage induced by heat
Carnitine partially protects the rat testis against the late damage produced by doxorubicin administered during pre-puberty
Protection by Hydrogen Against Gamma Ray-Induced Testicular Damage in Rats
Protective Effects of the Fermented Milk Kefir on X-Ray Irradiation-Induced Intestinal Damage in B6C3F1 Mice
Fertility preservation strategies for male patients with cancer
Protection by L-carnitine against radiation-induced ileal mucosal injury in the rat: Pattern of oxidative stress, apoptosis and cytokines
Enhanced mitophagy in Sertoli cells of ethanol-treated rats: morphological evidence and clinical relevance
Effects of L-carnitine and L-acetyl-carnitine on testicular sperm motility and chromatin quality
Distribution of Zonula Occludens-1 and Occludin and alterations of testicular morphology after in utero radiation and postnatal hyperthermia in rats
Protective effects of thymoquinone on the neuronal injury in frontal cortex after chronic toluene exposure
The possible role of L-carnitine on the skeletal muscle of ovariectomized rats
A review of the logistic role of l-carnitine in the management of radiation toxicity and radiotherapy side effects

Topcu-Tarladacalisir Y, Kanter M, Uzal MC. Role of L-carnitine in the prevention of seminiferous tubules damage induced by gamma radiation: a light and electron microscopic study. Arch Toxicol 83: 735-746, 2009.

22
ATIF

ATIFLAR

Protective effects of L-carnitine on X irradiation-induced uterus injury via antioxidant and anti-inflammatory pathways
Drosophila Lysophospholipase Gene swiss cheese Is Required for Survival and Reproduction
Ameliorative effect of L-carnitine on lambda-cyhalothrin-induced anatomical and reproductive aberrations in albino mice
Manipulation of fatty acid profiles in roosters' testes, alteration in sexual hormones, improvements in testicular histology characteristics and elevation sperm quality factor by L-carnitine Mohammadi, V; Sharifi, SD; (...); Alizadeh, A Feb 2021 | THERIOGENOLOGY 161 , pp.8-15
Effects of telmisartan and losartan on irradiated testes
Effects of Anticancer Drugs in Reproductive Parameters of Juvenile Male Animals and Role of Protective Agents (Mart 2017)
Evaluation of serum level of Osteocalcin hormone in male infertility (Şubat 2017)
Potential Radioprotective Effect of AT(1) Receptor Antagonists Against Morphological and Ultrastructural Changes in the Testes Induced by Ionizing Radiation (Şubat 2017)
The Effects of l-Carnitine Against Cyclophosphamide-Induced Injuries in Mouse Testis (Şubat 2017)
Evaluation of the Fas/FasL signaling pathway in diabetic rat testis
The protective effect of regucalcin against radiation-induced damage in testicular cells
Protective effect of L-carnitine in cyclophosphamide-induced germ cell apoptosis
L-Carnitine protects against testicular dysfunction caused by gamma irradiation in mice
The Protective Effects of Acetyl L-Carnitine on Testis Gonadotoxicity Induced by Cisplatin in Rats
Food, Nutrigenomics, and Neurodegeneration-Neuroprotection by What You Eat!
Spermatogonial behavior in rats during radiation-induced arrest and recovery after hormone suppression
Distribution of Zonula Occludens-1 and Occludin and alterations of testicular morphology after in utero radiation and postnatal hyperthermia in rats
The alteration of asymmetric dimetilarginine (ADMA) levels in cardiac and gastrocnemius muscles following radioactive iodine application in guinea pigs and the effect of L-carnitine on this alteration
A review of the logistic role of l-carnitine in the management of radiation toxicity and radiotherapy side effects
Antiapoptotic effect of l-carnitine on testicular irradiation in rats
The Effect of Orally Administered L-carnitine on Testis Tissue, Sperm Parameters and Daily Sperm Production in Adult Mice
Ionizing radiation modulates the surface expression of human leukocyte antigen-G in a human melanoma cell line

Tarladacalisir TY, Kanter M, Uygun M. Protective effects of vitamin c on cisplatin-induced renal damage: A light and electron microscopic study. Renal Failure, 30: 1-8, 2008.

23
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Pharmacological Effects of Cisplatin Combination with Natural Products in Cancer Chemotherapy
Nephroprotective effect of Rudgea viburnoides (Cham.) Benth leaves on gentamicin-induced nephrotoxicity in rats (Şubat 2017)
Riboflavin Arrests Cisplatin-Induced Neurotoxicity by Ameliorating Cellular Damage in Dorsal Root Ganglion Cells M Salman, I Naseem, I Hassan, AA Khan… - BioMed Research
Icodextrin reduces insulin resistance in non-diabetic patients undergoing automated peritoneal dialysis: results of a randomized controlled trial (STARCH) TP de Moraes, MCC Andreoli, ME Canziani… - Nephrology Dialysis
Protective effect of CV247 against cisplatin nephrotoxicity in rats
The Protective Effect of Curcumin on Hepatotoxicity and Ultrastructural Damage Induced by Cisplatin
The Potential Role of Azadirachta indica Treatment on Cisplatin-Induced Hepatotoxicity and Oxidative Stress in Female Rats
POMEGRANATE SEED EXTRACT ATTENUATES CHEMOTHERAPY-INDUCED LIVER DAMAGE IN AN EXPERIMENTAL MODEL OF RABBITS
The Protective Effect of Melatonin and Agomelatin against Cisplatin-Induced Nephrotoxicity and Oxidative Stress in the Rat Kidney
Cisplatin-Induced Neurotoxicity In Vivo Can Be Alleviated by Riboflavin Under Photoillumination
The effect of intratympanic vitamin C administration on cisplatin-induced ototoxicity
Cisplatin: an old drug with a newfound efficacy - from mechanisms of action to cytotoxicity
CARVEDILOL PROTECTS AGAINST APOPTOTIC CELL DEATH INDUCED BY CISPLATIN IN RENAL TUBULAR EPITHELIAL CELLS
Administration of vitamin E and losartan as prophylaxes in cisplatin-induced nephrotoxicity model in rats
Cisplatin-induced nephrotoxicity and targets of nephroprotection: an update
A Combination of Vitamin C and Losartan for Cisplatin-induced Nephrotoxicity in Rats
Cytotoxic effect of Ochratoxin A on the renal corpuscles of rat kidney: could Ochratoxin A cause kidney failure?
Protective Effect of Flaxseed Oil on Renal Injury in Hyperlipidaemic Rats: The Effect of Flaxseed Oil on Hyperlipidaemia
Pomegranate Seed Extract Attenuates Chemotherapy-Induced Acute Nephrotoxicity and Hepatotoxicity in Rats
Ameliorative effect of riboflavin on the cisplatin induced nephrotoxicity and hepatotoxicity under photoillumination
Cisplatin induces duplex 3 ' overhangs and 5 ' blunt ends in epididymal epithelium in a Bax-dependent manner without any protection from L-ascorbic acid
Protective effect of L-carnitine against cisplatin-induced liver and kidney oxidant injury in rats
Vitamin C protects against ionizing radiation damage to goblet cells of the ileum in rats

Uluslararası Hakemli Dergilerde Yayınlanan Makaleler

Sözüer EC, Topcu-Tarladacalisir Y. Quercetin Ameliorates the Streptozotocin-Induced Diabetic Renal Injury by Inhibiting Apoptosis. Trakya University Journal of Natural Sciences, 22(2): 131-138, 2021.

Beneficial Effects of Quercetin on the Zone of Stasis in an Experimental Burn Model

Kanter M, Aksu B, Akpolat M, Tarladaçalışır TY, Aktas C, Uysal H. Vitamin e protects against oxidative damage caused by cadmium in the blood of rats. EJGM 6(3):154-160, 2009.

Uluslararası Bilimsel Toplantılarda Sunulan ve Bildiri Kitabında Basılan Bildiriler (Proceedings)

Mercan Z, Topcu-Tarladacalisir Y. “Trinitrobenzen sülfonik asit ile oluşturulan deneysel kolit modelinde quercetinin otofajik sürece etkisi” 6. Uluslararası Gap Matematik-Mühendislik-Fen Ve Sağlık Bilimleri Kongresi Kongre Özet Kitabı, Şanlıurfa 2021.

Y. T. TOPÇU, M. M. SAPMAZ, T. KARACA, Effects of curcumin on renal tubular cell apoptosis and related pathways in cisplatininduced Nephrotoxicity, 15th International Congress of Histochemistry and Cytochemistry

Ö. YAMAN, Y. T. TOPÇU, L-Carnitine counteracts prepubertal exposure to cisplatin-induced impaired sperm in adult rats by preventing germ cell apoptosis, 1th International Health Sciences Congress

M. M. SAPMAZ, K. TABAKÇIOGLU, Y. T. TOPÇU, H. Y. UZ, I. Ö. KURT, D. MURATOGLU, Dehp induced oxidative alterations in relation to DNA damage and proliferation in the rat liver, 15th International Congress of Histochemistry and Cytochemistry

H. Y. UZ, M. M. SAPMAZ, Y. T. TOPÇU, G. Ö. KIZILAY, T. KARACA, S. ÇIKMAZ, Protective Effects of Quercetin and Resveratrol Against Gentamicin-Induced Nephrotoxicity in Rats: Role of Nuclear Factor-Kappa B Pathway, 15th International Congress of Histochemistry and Cytochemistry

M. Sapmaz-Metin, Y. Topcu-Tarladacalisir, Y.H. Uz, M. Inan, I. Kurt Omurlu, A. Cerkezkayabekir, G. Kızılay, M. Akpolat, T. Karaca, “Allopurinol ameloriates ischemia-reperfusion injury in ovarian torsion-detorsion subjected rats”, Microscopy Conference 2013, Regensburg, Germany, Abstract Book, P-559, 25-30 Aug 2013.

Y. Topcu-Tarladacalisir, T. Tarladacalisir, M. Sapmaz-Metin, A. Karamustafaoglu, Y.H. Uz, M. Akpolat, A. Cerkezkayabekir, F.N. Turan, “N-acetylcysteine counteracts oxidative stres and protects alveolar epithelial cells from lung contusion-induced apoptosis in rats with blunt chest trauma”, Microscopy Conference 2013, Regensburg, Germany, Abstract Book, P-553, 25-30 Aug 2013.

M. Sapmaz-Metin, Y. Topcu-Tarladacalisir, Y.H. Uz, M. Inan, I. Kurt Omurlu, A. Cerkezkayabekir, G. Kızılay, M. Akpolat, T. Karaca, “Allopurinol ameloriates ischemia-reperfusion injury in ovarian torsion-detorsion subjected rats”, Microscopy Conference 2013, Abstract Book, 147 (P-72), Regensburg, Germany, 25-30 Aug 2013.

Y. Topcu-Tarladacalisir, T. Tarladacalisir, M. Sapmaz-Metin, A. Karamustafaoglu, Y.H. Uz, M. Akpolat, A. Cerkezkayabekir, F.N. Turan, “N-acetylcysteine counteracts oxidative stres and protects alveolar epithelial cells from lung contusion-induced apoptosis in rats with blunt chest trauma”, Microscopy Conference 2013, Abstract Book, 143 (P-70), Regensburg, Germany, 25-30 Aug 2013.

M. Kanter, Y. Topcu-Tarladacalisir, S. Parlar, “Antiapoptotic effect of L-carnitine on testicular irradiation in rats”, The International Cell Death Society Symposium “Multidisciplinary Approaches in Cell Death Research From Yeast to Man”, Antalya, Turkey, Abstract Book, P-32, 28-31 May 2010

M. Akpolat, Y. Topcu-Tarladacalisir, M. Kanter, “Protective effects of curcumin and vitamin C on ionizing radiation-induced morphological destruction of intestinal mucosa in rats”, VIII. International Symposium of Clinical Anatomy, Supplement to Scripta Scientifica Medica, Vol. 40, 1, Varna, Bulgaria, 10-12 October 2008.

G. Kizilay, Y. Topcu-Tarladacalisir, Y.H. Uz, M. Akpolat, M. Sapmaz, “Testicular damages in diabetes mellitus: A light and electron microscopic study”, VIII. International Symposium of Clinical Anatomy, Supplement to Scripta Scientifica Medica, Vol. 40, 66, Varna, Bulgaria, 10-12 October 2008.

Y. Topcu-Tarladacalisir, M. Kanter, M.C. Uzal, “Role of L-carnitine in the Prevention of Seminiferous Tubules Damage Induced by Gamma Radiation: A Light and Electron Microscopic Study”, VIII. International Symposium of Clinical Anatomy, Supplement to Scripta Scientifica Medica, Vol. 40, 96, Varna, Bulgaria, 10-12 October 2008.

Ulusal Hakemli Dergilerde Yayınlanan Makaleler

Uz Y., Kızılay G., Akpolat M., Topcu-Tarladaçalışır Y., Sapmaz-Metin M. Adriyamisin sıçan/fare modeli ve embriyolojide önemi. Düzce Tıp Dergisi. 14(2):51-56, 2012.

Akpolat M., Topcu-Tarladaçalışır Y., Uz Y., Sapmaz-Metin M., Kızılay G. Kanser tedavisinde curcuminin yeri. Yeni Tıp Dergisi. 27: 142-147, 2010.

2
ATIF

Akpolat M., Tarladaçalışır TY., Kanter M. İyonizan radyasyonun neden olduğu ince bağırsak hasarına karşı curcumin ve c vitamininin koruyucu etkilerinin incelenmesi. Tıp Araştırma Dergisi. 6(2): 77-85, 2008.

Kanter M., Tarladaçalışır TY., Akpolat M., Mercantepe T. Gamma radyasyona bağlı oluşan jejunum mukoza hasarına karşı curcumin ve amifostinin koruyucu etkilerinin incelenmesi. Tıp Araştırma Dergisi. 6(3): 128-135, 2008.

Kanter M, Tarladaçalışır TY, Uygun M. Cisplatin nefrotoksisitesinde e vitamininin koruyucu etkileri: Işık ve elektron mikroskopik çalışma. Tıp Araştırma Dergisi. 5(3): 83-90, 2007.

1
ATIF

Topçu Y., Uygun M., Akpolat M., Uz HY. E ve c vitaminlerinin cisplatin hepatotoksisitesini önlemedeki etkilerinin histolojik olarak incelenmesi. Trakya Üniversitesi Tıp Fakültesi Dergisi, 22(3):124-31, 2005.

Ulusal Bilimsel Toplantılarda Sunulan ve Bildiri Kitabında Basılan Bildiriler

121 - Di (2-Ethylhexyl) Phthalate (DEHP) Maruziyetinde, Prepubertal, Erişkin ve Overektomize Dişi Ratların Uterus Dokularında Oksidatif ve Proliferatif Parametrelerdeki Değişikliklerin İncelenmesi

Quercetin attenuates endoplasmic reticulum stress‐mediated apoptosis in TNBS‐induced colitis

S. Bayram, G. Kızılay, Y. Topçu-Tarladaçalışır. “Deneysel diyabetik sıçan testis dokularında Fas/Fas-L sinyal yolağının rolü. 22. Elektron Mikroskopi Kongresi (EMK 2015) p49, İstanbul, 02-04 Eylül, 2015. (Eylül 2015)

Y. Bozdemir Dönmez, Kızılay G, Topcu-Tarladaçalışır Y. Diyabetik Testis Dokusunda JNK ve ERK nın Rolleri. XII. Ulusal Histoloji ve Embriyoloji Kongresi p082, Ankara, 27-31 Mayıs, 2014

Sapmaz Metin, M., Topçu Tarladaçalışır, Y., Karaöz, B., Ünsal Atan, Şenay., “Subkronik ve kronik kadmiyum maruziyetinin uterus histolojisi üzerine etkileri”, XII. Ulusal Histoloji-Embriyoloji Kongresi, Ankara, 27-31 Mayıs, 2014.

M. Sapmaz-Metin, Y. Topçu-Tarladaçalışır, Y.H. Uz, M. Inan, İ. Kurt Ömürlü, A. Çerkezkayabekir, G. Kızılay, M. Akpolat, “Torsiyon-detorsiyon uygulanmış rat ovaryumlarında e vitamininin apoptozis ve c-Jun N terminal kinaz aktivitesi üzerine etkileri. XXI. Ulusal Elektron Mikroskopi Kongresi (Uluslararası katılımlı). Mersin, Türkiye Sözlü bildiri S8, 28-31 Mayıs 2013.

M. Akpolat, K. Gülle, Y. Topçu-Tarladaçalışır, Z. Safi-Öz, B.H. Bakkal, M. Araslı, Ü. Özel-Türkçü, “Radyasyona bağlı oluşan ileum mukoza hasarına karşı l-karnitin ile koruma: oksidatif stres, apoptozis ve sitokinlerin düzenlenimi” XXI. Ulusal Elektron Mikroskopi Kongresi (Uluslararası katılımlı), Mersin, Türkiye, P168, 28-31 Mayıs 2013.

Y. Topçu-Tarladaçalışır, M. Akpolat, Y.H. Uz, G. Kızılay, M. Sapmaz Metin, A. Çerkezkayabekir, İ. Kurt Ömürlü, “Asetik asit ile oluşturulan deneysel kolit modelinde curcuminin antiapoptotik etkisi: fosfo-c-jun n-terminal kinaz ve fosfo-p38 mitojen aktive eden protein kinazların rolü”, XXI. Ulusal Elektron Mikroskopi Kongresi (Uluslararası katılımlı), Mersin, Türkiye, P137, 28-31 Mayıs 2013.

M. Akpolat, K. Gülle, Y. Topçu-Tarladaçalışır, Z. Safi-Öz, B.H. Bakkal, M. Araslı, Ü. Özel-Türkçü, “Deneysel radyasyon enteritinde L-karnitinin profilaktik kullanımı MCP-1, IFN-γ ve TNF-α düzeylerini nasıl etkiler?”, Uluslararası Katılımlı X. Ulusal Histoloji ve Embriyoloji Kongresi, Denizli, Türkiye. Cell and Tissue Biology Research, Volume/2012 Supplement, P008, 67-68. 16-19 May 2012.

M. Kanter, Y. Topçu-Tarladaçalışır, M. Akpolat, F.N. Turan, “Non-alkolik yağlı karaciğer hastalığında keten tohumu yağının hipolipidemik etkileri”, Uluslararası Katılımlı X. Ulusal Histoloji ve Embriyoloji Kongresi, Denizli Türkiye. Cell and Tissue Biology Research, Volume/2012 Supplement, P210, 63-64. 16-19 Mayıs 2012.

Y. Topçu-Tarladaçalışır, M. Akpolat, Y.H. Uz, G. Kızılay, M. Sapmaz-Metin, A. Çerkezkayabekir, İ. Kurt-Ömürlü, “Asetik asit ile oluşturulan deneysel kolit modelinde curcuminin apoptozis üzerine etkisi”, 20. Ulusal Elektron Mikroskopi Kongresi (Uluslararası Katılımlı) Kemer, Türkiye, Sözlü Bildiri SB-10, 25-28 Ekim 2011.

M. Kanter, Y. Topçu-Tarladaçalışır, C. Uzal, “Sıçanlarda radyasyona bağlı akut ve geç renal hasarın önlenmesinde amifostinin rolü: Histopatolojik çalışma”, X. Ulusal histoloji ve embriyoloji kongresi (Uluslararası katılımlı), İzmir, Türkiye, Sözlü Bildiri T-141, 17-20 Mayıs 2010

M. Akpolat, M. Kanter, Y. Topçu-Tarladaçalışır, N. Aydoğdu, “Keten tohumu yağının hiperlipidemiye bağlı oluşan böbrek hasarı üzerine koruyucu etkisinin incelenmesi”, Uluslararası Katılımlı X. Ulusal Histoloji ve Emriyoloji Kongresi, Çeşme, Türkiye, Sözlü Bildiri T-49. Cell and Tissue Biology Research. 2 No: 1(S), 113, 17-20 May 2010.

M. İnan, Y.H. Uz, G. Kızılay, Y.T. Tarladaçalışır, M.S. Metin, M. Akpolat, N. Aydoğdu, “Bağırsak iskemi reperfüzyonu sonucu karaciğerde oluşan hasara karşı sildenafilin koruyucu etkisi”, XVIII. Ulusal Çocuk Cerrahisi Kongresi, Antalya, Türkiye, Sözlü Bildiri SB53. Çocuk Cerrahisi Dergisi, 92, 22-25 Eylül 2010.

Y. Topçu, M. Uygun, M. Akpolat, Y.H. Uz, “Cisplatine bağlı karaciğer hasarını önlemede E ve C vitamini etkilerinin ışık ve elektron mikroskopik düzeylerde incelenmesi”, VII. Ulusal Histoloji ve Embriyoloji Kongresi, Özet Kitabı, 189, Mersin, Türkiye, 18-21 Mayıs 2004.

Y. Topçu, Uygun M. Cisplatinin oluşturduğu böbrek hasarlarında E ve C vitamini etkilerinin ışık ve elektron mikroskopik düzeylerde incelenmesi. XVI Ulusal elektron mikroskopi kongresi (Uluslararası katılımlı), Özet Kitabı, P-22, İzmir, Türkiye, 2-5 Eylül 2003.

Ulusal Konferans ve Sempozyumlar

26. uLUSAL ELEKTRON MİKROSKOBİ KONGRESİ

Yazılan Ulusal Kitaplar veya Kitaplarda Bölümler

Uz YH, Y. Topçu Tarladaçalışır: Sindirim Sistemi I: Oral Kavite ve İlişkili Yapılar B Baykal (Çeviri Editörü). Histoloji, Konu Anlatımı ve Atlas (Histology Text and Atlas, Ross MH and Pawlina W). Ankara, Palme, 2014: 526-567.

Yönetilen Yüksek Lisans Tezleri

Trinitrobenzen Sülfonik Asit ile Oluşturulan Deneysel Kolit Modelinde Quercetin Kullanımının Otofajik Sürece Etkisi (2019)

Deneysel Diyabet Oluşturulmuş Sıçan Böbrek Dokusunda Quercetinin Koruyucu Etkisinin İncelenmesi

Prepubertal sıçan testislerinde cisplatin maruziyetinin neden olduğu seminifer tübül hasarı ve erişkin sperm parametreleri üzerine L-Karnitinin koruyucu etkisi (Kasım 2015)

Üye Olunan Kurum ve Kuruluşlar

European Association for Cancer Research (EACR)
Türk Elektron Mikroskobu Derneği
Türk Histoloji ve Embriyoloji Derneği

Yapılan Hakemlikler

DOÇENTLİK EKİM 2023
DOÇENTLİK MART DÖNEMİ
2022 ekim dönemi
SDÜ Sağlık Bilimleri Dergisi, 2022
Journal of research in pharmacy, 2022.
Clinical and Experimental Health Sciences, 2022.
Balkan Medical Journal, 2022.
Drug and chemical toxicology
Journal of Visualized Experiments, 2021
Drug and chemical toxicology, 2021
Biotechnic and histochemistry, 2021
SDÜ Sağlık Bilimleri Dergisi, 2018
Osmangazi Tıp Dergisi, 2018
Batı Karadeniz Tıp Dergisi 2018
LDCT-2018
SDÜ Sağlık Bilimleri Dergisi, 2017.
SDÜ Sağlık Bilimleri Dergisi, 2017.
Batı karadeniz Tıp dergisi, 2017.
Applied Biochemistry and Biotechnology, 2017
Food and Chemical Toxicology, 2017
BalkMedJ-2015
Histology and Histopathology
International Journal of Pharmacy and Pharmacology, 2013
Renal Failure 2008

Projeler

TUBAP 208/123: Deneysel Kolit Modelinde Endoplazmik Retikulum Stresi Üzerine Quercetinin Etkisinin İncelenmesi” 2020.

TUBİTAK (117S452) Sitagliptin Tedavisi Uygulanan Diyabetik Sıçan Testis Dokularında Fukoidanın Etkileri”,2019 (Eylül 2019)

TUBAP 208/207: Trinitrobenzen Sülfonik Asit ile Oluşturulan Deneysel Kolit Modelinde Quercetin Kullanımının Otofajik Sürece Etkisi

TUBAP 2017/128: Deneysel Diyabet Oluşturulmuş Sıçan Böbrek Dokusunda Quercetinin Koruyucu Etkisinin İncelenmesi” 2018.

TÜBITAK PROJESI, Di (2-Ethylhexyl) Phthalate Maruziyetinde Prepubertal, Eriskin ve Ovariektomize Disi Ratlarin Karaciger Dokularinda Oksidatif Stres ve Apoptotik Parametrelerin Karsilastirilmasi, (Mart 2017)

NKUBAP (00.20.AR.15.0) Kersetinin Ratlarda, Yanık Staz Bölgesi Üzerindeki Etkisi., 2017. (Şubat 2017)

TUBAP 2013/124: Fas/FasL Yolağının Diyabetik Erkek İnfertilitesindeki Rolünün Değerlendirilmesi. 2015.

TUBAP 2014/87: Prepubertal sıçan testislerinde cisplatin maruziyetinin neden olduğu seminifer tübül hasarı ve erişkin sperm parametreleri üzerine L-Karnitinin koruyucu etkisi Proje Yöneticisi

TUBİTAK (113S831) Cisplatin nefrotoksisitesinde curcuminin apoptozis ve oksidoinflamatuar durum üzerine etkileri: p53, p38 ve JNK protein kinazların rolü, Proje yürütücüsü

TÜBAP/2014/78- Histoloji-Embriyoloji Anabilim Dalı Uygulama Pratik Ders Salonunun Yeniden Düzenlenmesi, Yardımcı araştırmacı, 2014.

TÜBAP/2014/77- Histoloji- Embriyoloji Anabilim Dali Uygulama Pratik Ders Salonuna Monitör Kurulmasi, Yardımcı araştırmacı, 2014.

TÜBAP 2012/90: “Deneysel akciğer kontüzyonunda N-asetil sistein ve metilprednizolonun apoptozis ve oksidoinflamatuar durum üzerine etkileri” Proje Yürütücüsü

TÜBAP 2011/121: “Ovaryum torsiyon-detorsiyon modelinde allopurinol ve E vitamininin apoptozis üzerine etkileri: p38 ve Jnk protein kinazlarının rolü” Yardımcı araştırmacı

TÜBAP 2009/154: “Asetik asit ile oluşturulan deneysel kolit modelinde curcuminin apoptozis üzerine etkisi” Proje Yürütücüsü 2011.

(TÜBAP) 2008/116: “Deneysel Diabet Oluşturulmuş Sıçanların Testis Dokularında MAPK İmmünreaktivitesinin İncelenmesi” Yardımcı araştırmacı, 2008-2010.

TÜBAP 2008-72: “Keten Tohumu Yağının Hiperlipidemiye Bağlı Oluşan Böbrek Hasarı Üzerine Koruyucu Etkisinin İncelenmesi” Yardımcı araştırmacı 2010

(TÜBAP) 444: “Cisplatinin oluşturduğu böbrek korteks hasarlarında E ve C vitamini etkilerinin ışık ve elektron mikroskopik düzeylerde incelenmesi

Diğer

Doçentlik unvan sınavı jüri üyeliği yapmak (rapor yazmak koşulu ile) (Mart 2022)

İstanbul Sağlık ve Teknoloji Üniversitesi Tıp Fakültesi Histoloji ve Embriyoloji AD Doktor öğretim üyesi jüriliği

Kırklareli Üniversitesi Tıp Fakültesi Histoloji ve Embriyoloji AD Doktor öğretim üyesi jüriliği
Doçentlik unvan sınavı jüri üyeliği yapmak (rapor yazmak koşulu ile) (Mart 2020)
Doçentlik unvan sınavı jüri üyeliği yapmak (rapor yazmak koşulu ile) (Ekim 2019)

» Eğitim Durumu

Lisans » 2000 Yılı mezunu

Yüksek Lisans » 2003 Yılı mezunu

Yüksek Lisans Tezi;

Doktora » 2008 Yılı mezunu

Doktora Tezi;

» Akademik Unvanlar

Araştırma Görevlisi » 2001 Yılında

Yardımcı Doçent Doktor » 2013 Yılında

Doçent Doktor » 2014 Yılında

Profesör Doktor » 2019 Yılında

» Akademik ve İdari Görevler

Tıp Fakültesi Ders Programı

Tıp Fakültesi

Tıp Fakültesi Ders Programı

Tıp Fakültesi Ders Programı

Tıp Fakültesi Ders Programı

Tıp Fakültesi

Tıp Fakültesi

Tıp Fakültesi

Tıp Fakültesi

Tıp Fakültesi

Türkiye Klinikleri Dergileri / Türkiye Klinikleri Dergileri

Türk Histoloji ve Embriyoloji Derneği / Türk Histoloji ve Embriyoloji Derneği

Sağlık Bilimleri Enstitüsü / Sağlık Bilimleri

Sağlık Bilimleri Enstitüsü / Sağlık Bilimleri Enstitüsü

Bülent Ecevit Üniversitesi / Tıp Fakültesi

» Yayınlar

SCI-SSCI, SCI Expanded ve AHCI Kapsamındaki Yayınları

Uluslararası Hakemli Dergilerde Yayınlanan Makaleler

Uluslararası Bilimsel Toplantılarda Sunulan ve Bildiri Kitabında Basılan Bildiriler (Proceedings)

Ulusal Hakemli Dergilerde Yayınlanan Makaleler

Ulusal Bilimsel Toplantılarda Sunulan ve Bildiri Kitabında Basılan Bildiriler

Ulusal Konferans ve Sempozyumlar

Yazılan Ulusal Kitaplar veya Kitaplarda Bölümler

Yönetilen Yüksek Lisans Tezleri

Üye Olunan Kurum ve Kuruluşlar

Yapılan Hakemlikler

Projeler

Diğer