» Eğitim Durumu

» Akademik Unvanlar

» İş Tecrübesi

» Yayınlar

SCI-SSCI, SCI Expanded ve AHCI Kapsamındaki Yayınları

  • Investigation of the Genetic Etiology in Idiopathic Generalized Epileptic Disorders by Targeted Next-generation Sequencing Technique (Ocak 2023)
  • Prenatal diagnosis and molecular cytogenetic characterization of partial dup (18p)/del (18q) due to a maternal pericentric inversion 18 in a foetus with multiple anomalies (Mart 2022)
  • First Report of Jacobsen Syndrome with Dextrocardia Diagnosed with del (11)(q24q25) (Mart 2022)
  • Comprehensive Genetic Analysis of RASopathy in the Era of Next-Generation Sequencing and Definition of a Novel Likely Pathogenic KRAS Variation
  • The evaluation of risk factors leading to early deaths in patients with acute promyelocytic leukemia: a retrospective study
  • Customised targeted massively parallel sequencing enables more precise diagnosis of patients with epilepsy
  • Chronic myeloid leukaemia after chemoradiotherapy for solid malignancies
  • Targeted next-generation sequencing as a diagnostic tool in gastrointestinal system cancer/polyposis patients
  • Otizm Spektrum Bozukluğu ile FOXP2, GRIN2B, KATNAL2 ve GABRA4 Genlerinin İlişkisinin Araştırılması
  • Prenatal diagnosis of 20p13 microdeletion syndrome
  • A Pilot Study of Identification Genetic Background of Craniosynostosis Cases
  • Comprehensive Genetic Analysis Results of TSC1/TSC2 Genes in Patients with Clinical Suspicion of Tuberous Sclerosis Complex and Definition of 3 Novel Variants
  • Targeted High-Throughput Sequencing Analysis Results of Osteogenesis Imperfecta Patients from Different Regions of Turkey
  • The importance of targeted next-generation sequencing usage in cytogenetically normal myeloid malignancies
  • The Importance of Multiple Gene Analysis for Diagnosis and Differential Diagnosis in Charcot Marie Tooth Disease
  • The application of next generation sequencing maturity onset diabetes of the young gene panel in Turkish patients from trakya region
  • Wiedemann-Steiner syndrome as a differential diagnosis of Cornelia de Lange syndrome using targeted next-generation sequencing: a case report
  • A Rare Case of Mosaic Unbalanced Non-Robertsonian Translocation Involving Chromosomes 15 and 22 with Congenital Abnormalities in Monozygotic Twins
  • Distal 3p Duplication and 22q13. 3 Deletion with Severe Hypotonia Originating from a Paternal Balanced Translocation (3; 22)
  • A Child with 5q Deletion and Accompanying Chiari 1 Malformation
  • Chromosomal microarray analysis in Turkish patients with unexplained developmental delay and intellectual developmental disorders
  • Pros and cons for fluorescent hybridization, karyotyping and next generation sequencing for diagnosis and follow-up of multiple myeloma
  • Genetic screening results of individuals with high risk BRCA-related breast/ovarian cancer in Trakya region of Turkey
  • Long-range cis-regulatory elements controlling GDF6 expression are essential for ear development
  • Concepts of double hit and triple hit disease in multiple myeloma, entity and prognostic significance
  • An unknown chromosomal aberration in a patient with chronic lymphocytic leukemia: Extra isochromosome 4q (Mart 2019)
  • FOXF2 is required for cochlear development in humans and mice (Aralık 2018)
  • Prenatal diagnosis of a new case:De novo balanced non-Robertsonian translocation involving t(15;22)(p11.2;q11.2) (Aralık 2018)
  • A large posterior encephalocele associated with severe ventriculomegaly, cerebellar atrophy and transposition of the great arteries (Haziran 2018)
  • Prenatal diagnosis of chromosomal polymorphisms: most commonly observed polymorphism on Chromosome 9 have associations with low PAPP-A values (Aralık 2017)
  • Identification of a novel homozygous TBC1D24 mutation in a Turkish family with DOORS syndrome. (Aralık 2017)
  • Görker I,Gürkan H, Demir Ulusal S, Atlı E, Ikbal Atlı E. DOI: 10.1515/bjmg-2016-0041 A 9-YEAR-OLD-GIRL WITH PHELAN McDERMID SYNDROME, WHO HAD BEEN DIAGNOSED WITH AN AUTISM SPECTRUM DISORDER (Ocak 2017)
    1
    ATIF
  • Cihan Inan, N. Cenk Sayın, Emine Atlı, Selma Ulusal, Selen Erzincan, Isil Uzun, Hakan Gurkan & Füsun G. Varol show less Pages 339-343 Published online: 16 Jun 2016 Tetrasomy 18p in a Twin Pregnancy with Diverse Expression in Both Fetuses (Mayıs 2016)
    1
    ATIF
  • Eİ Atli, H Gürkan, Ü Vatansever, S Ulusal, H Tozkir Balkan Journal of Medical Genetics 18 (2), 77-82 A CASE WITH EMANUEL SYNDROME:EXTRA DERIVATIVE 22 CHROMOSOME INHERITED FROM THE MOTHER (Nisan 2016)
  • R Kalkan, E Atli - Critical Reviews™ in Eukaryotic Gene Expression Volume 26, 2016 Issue 2 pages 137-142 The impacts of miRNAs in Glioblastoma Progression, Treatment and Prognosis (Mart 2016)
    1
    ATIF
  • Eİ Atli, R Kalkan, M Özdemir, HE Aydın, A Arslantaş, S Artan African Health Sciences 16 (1), 218-226 RARβ gene methylation is a candidate for primary glioblastoma treatment planning. (Mart 2016)
    1
    ATIF
  • R Kalkan, Eİ Atli, M Özdemir, E Çiftçi, HE Aydin, S Artan, A Arslantaş Gene 554 (1), 81-86 IDH1 mutations is prognostic marker for primary glioblastoma multiforme but MGMT hypermethylation is not prognostic for primary glioblastoma multiforme (Ocak 2015)
    8
    ATIF
  • EI Atli, R Kalkan, E Ciftci, E ÖZKARA, O ÇİLİNGİR, M ÖZDEMİR, Z ÖZBEK, ... Journal of Neurological Sciences 31 (4) IDH2 Mutations in Primary Glioblastoma (Eylül 2014)

Uluslararası Hakemli Dergilerde Yayınlanan Makaleler

  • The Frequency of SMN1, SMN2 Copy Numbers in 246 Turkish Cases Analyzed with MLPA Method (Şubat 2023)
  • Genotype-phenotype correlations of pathogenic copy number variations on X chromosome detected by comparative genomic hybridization (Eylül 2022)
  • Investigation of genetic alterations in congenital heart diseases in prenatal period
  • RETROSPECTIVE ANALYSIS OF ALPHA GLOBIN COPY NUMBER VARIATIONS DETERMINED BY MLPA IN THE TRAKYA REGION
  • Germline pathogenic variants identified by targeted next-generation sequencing of susceptibility genes in pheochromocytoma and paraganglioma
  • Investigation the Relationship of Autism Spectrum Disorder and FOXP2, GRIN2B, KATNAL2, GABRA4 Genes
  • Clinical features of aberrations chromosome 22q: a pilot study
  • Investigation the etiology of syndromic autism with targeted gene analysis
  • Two Novel Pathogenic FBN1 Variations and Their Phenotypic Relationship of Marfan Syndrome
  • De Novo Subtelomeric 6p25.3 Deletion with Duplication of 6q23.3-q27: Genotype–Phenotype Correlation (Haziran 2019)
  • EI Atli, H Gurkan, H Tozkir, Y Ozen, S Ulusal JFIV Reprod Med Genet 4, 189 Tekrarlayan Gebelik Kaybı Öyküsü Taşıyan Çiftlerin Trombofili Gen Mutasyon ve Sitogenetik Analizi (Ağustos 2016)
  • Atli EI, Yakicier C, Akin A (2016) Anaplastic Lymphoma Kinase (ALK) Rearrangement and EGFR Mutations in Lung Adenocarcinoma. Adv Oncol Res Treat 1:103. (Mart 2016)
  • Investigation on the Effects of Modifying Genes on the Spinal Muscular Atrophy Phenotype

Uluslararası Bilimsel Toplantılarda Sunulan ve Bildiri Kitabında Basılan Bildiriler (Proceedings)

  • Boy Kısalığı Olan Hastalarda Kopya Sayısı Değişimleri (Ekim 2019)
  • Farklı Olgularda Nadir Gözlenen X Kromozomu Değişimleri (Ekim 2019)
  • Copy Number Variation (CNV) in Patients Diagnosed with Growth Retardation (Temmuz 2019)
  • Prenatal management and pregnancy outcomes in fetuses with cystic hygroma (Nisan 2019)
  • A six - year retrospective study of amniocentesis: one centre experience (Nisan 2019)
  • A case of encephalocele (Haziran 2017)
  • ArrayCGH analysis in patients with intellectual disability/developmental delay in Turkish Children living in Trakya Region (Haziran 2017)
  • 3q22.2-q22.3 Deletion and 16p11.2 Microduplication Syndrome in a Patient with Blepharophimosis, Ptosis, Epicanthus Inversus Syndrome (Mayıs 2017)
  • E. I. Atlı, H. Gürkan, G. E. Pamuk, C. Akurut, H. Tozkır, A. M. Demir. A novel cytogenetic abberation is extra isochromosome 4q in chronic lymphocytic leukemia patient. European Human Genetics Conference-2016, (ESHG-2016). 21-24 May 2016, Conference venue: CCIB, Barcelona, Spain. E-P12.036 (Mayıs 2016) (Mayıs 2016)
  • Kalkan R.Atli EI,European Human Genetics Conference-2016, (ESHG-2016). 21-24 May 2016 The prognostic importance of the MGMT and RARβ gene hypermethylation in Primary Glioblastoma (Mayıs 2016)
  • E. Atli, H. Gurkan, S. Demir Ulusal, Y. Karal, E. I. Atli, H. Tozkir. A novel mutation of TBC1D24 identified in a Turkish family with DOORS syndrome. European Human Genetics Conference-2016, (ESHG-2016). 21-24 May 2016, Conference venue: CCIB, Barcelona, Spain. P11.051 (Mayıs 2016) (Mayıs 2016)
  • H. Gurkan, S. Demir Ulusal, H. Tozkır, E. Atlı, E. I. Atlı, D. Eker. Genetic screening for chromosomal abnormalities, Y chromosome microdeletions and copy number variation in infertile male patients living in the Trakya region of Turkey. European Human Genetics Conference-2016, (ESHG-2016). 21-24 May 2016, Conference venue: CCIB, Barcelona, Spain. P01.051 (Mayıs 2016) (Mayıs 2016)
  • Yasemim Özen, Hakan Gürkan, Ülfet Vatansever Özbek, Emine İkbal Atlı, Damla Eker, Betül Acunaş. A case report: 13q21-qter deletion with digital anomalies, duodenal atresia and anal atresia. 10th European Cytogenetics Conference 4 - 7 July 2015 Strasbourg Convention & Exhibition Centre Strasbourg, France (Temmuz 2015) (Temmuz 2015)
  • H. Gurkan, U. Vatansever, E. I. Atlı, D. Eker, S. Ulusal, N. A. Çiftdemir, H. Tozkır. Genotype-phenotype correlation in three patients with Wolf-Hirschhorn syndrome. European Human Genetics Conference. June 6 - 9, 2015 Glasgow, Scotland, United Kingdom, (Haziran 2015) (Haziran 2015)
  • Inan C, Sayın NC, Gurkan H, Erzincan SG, Ulusal S, Atlı EI, Varol FG. Both siblings affected by tetrasomy 18p in a dichorionic twin pregnancy. 14th World Congress in Fetal Medicine, 21-25 June 2015, Crete, Greece (Haziran 2015) (Haziran 2015)
  • R.Kalkan, E.I.Atli, IDH1 mutations in a Turkey series of primary glioblastoma, FEBS EMBO 2014 Conference, Paris, France, 30 August-4 September, 2014, FEBS Journal Volume 281 (Suppl. 1)(2014)65-783, P475 (Ağustos 2014)
  • E.İ. Atli, , R. Özkut, S. Artan, A. Arslantaş, M. Özdemir. European Journal of Cancer Volume 50, Supplement 4, May 2014,Pages e37,http://dx.doi.org/10.1016/j.ejca.2014.03.142 IDH2 mutations in Turkish patients with primary glioblastoma (Mayıs 2014)
  • E.İ. Atli, , R. Özkut, S. Artan, A. Arslantaş, M. Özdemir. European Journal of Cancer. Vol. 50, 05/2014; 50:e37. DOI: 10.1016/j.ejca.2014.03.144 RARβ methylation in Turkish patients with primary glioblastoma. (Mayıs 2014)
  • E.İ. Atli,M.C. Yakicier, A. Akin,European Journal of Cancer,Volume 50, Supplement 4, May 2014, Pages e37,6th Asian Oncology Summit and 10th Annual Conference of the Organisation for Oncology and Translational Research,P0097 ALK rearrangements in turkish patients with lung adenocarcinoma (Mayıs 2014)
  • E. I. Atli , R. Kalkan , S. Artan. FEBS Journal 281 (Suppl. 1) (2014) 65–783 IDH2 MUTATIONS IN TURKISH PATIENTS WITH PRIMAR GLIOBLASTOMA (Mayıs 2014)
  • E. I. Atli , R. Kalkan , S. Artan. FEBS Journal 281 (Suppl. 1) (2014) 65–783 4.RARB gene methylation in primary glioblastomas, (Mayıs 2014)

Uluslararası Konferans ve Sempozyumlar

  • Novel MID1 mutation in a patient with X-linked Opitz G/BBB syndrome (Nisan 2019)
  • Inan C, Sayin NC, Gurkan H, Atli E, Uzun I, Erzincan SG, Sutcu H, Dogan S, Atli EI, Varol FG. A Schizencephaly Case Accompanied By Deletion of Chromosome 22q13. 32. 15th World Congress in Fetal Medicine, Palma de Mallorca 2016 (Haziran 2016) (Haziran 2016)

Yazılan Uluslararası Kitaplar veya Kitaplarda Bölümler

  • Mechanisms of Aneuploidy
  • What Causes Down Syndrome?

Ulusal Hakemli Dergilerde Yayınlanan Makaleler

  • Y chromosome polymorphism in Turkish patients with reproductive problems: a genetic centre experience
  • Prenatal Sitogenetik Anormallikler ve Ultrasonografik olarak Saptanan Fetal Anomalilerin Korelasyonu (Mayıs 2022)
  • Inherited Variants is a Genetic Determinant of Mercaptopurine/Methotrexate Intolerance in Children With Acute Lymphoblastic Leukemia. (Nisan 2022)
  • HİPOTONİ TANILI ÇOCUK HASTALARDA GENOM KOPYA SAYISI VARYASYONLARININ ÖNEMİ
  • Sendromik Olmayan Konjenital Yarık Damak-Dudak Bulunan Hastalarda Kopya Sayısı Varyasyonlarının Belirlenmesi
  • Kardiyovasküler Hastalıkların Tanısında Yeni Nesil Dizi Analizi Yöntemi ile Genetik Varyasyonların Tespitinin Önemi
  • R KALKAN, Eİ ATLI Türk Nöroşirürji Dergisi 24 (3), 239-249 Geçmişten Günümüze Glioblastoma Genetiği (Haziran 2014)

Ulusal Bilimsel Toplantılarda Sunulan ve Bildiri Kitabında Basılan Bildiriler

  • Hakan Gürkan, Emine İkbal Atlı, Yasemin Özen, Beril Karabacak, Çisem Akurut, Cenk Sayın, Füsun Varol, Hilmi Tozkır. Evaluation Of Chromosomal And Thrombophilia Panel Of Recurrent Miscarriages. Uluslararası Katkılı ‘Gevher Nesibe Tıp Günleri 2016 ve Tıbbi Genetik ve Klinik Uygulamaları Kongresi. 11-13 Şubat 2016, KAYSERİ. Sözlü Sunum (Şubat 2016) (Şubat 2016)
  • Hilmi TOZKIR, Engin Atlı, Hakan GURKAN, Ulfet VATANSEVER OZBEK, Emine İkbal Atlı, Damla Eker, Ozge YAPICI UĞURLAR, Hakan GENCHELLAC, Betul ACUNAŞ. 1q23.3-q44 duplikasyonu ve Xq22.1-q28 delesyonu saptanan minör konjenital anomalileri olan bir yaşındaki kız olgu. 2.Ulusal Cocuk Genetik Sempozyumu/ 22-24 Ekim 2015, Samsun, (Ekim 2015) (Ekim 2015)
  • Hakan Gurkan, Engin Atlı, Ulfet VATANSEVER OZBEK, Emine İkbal Atlı, Damla Eker, Yasemin KARAL, Sumeyra DOĞAN, Hakan GENCHELLAC. De novo kromozom 11q14.1-11q22.2 delesyonu, hipotonisite, bilateral pitozis ve ekzoftalmus saptanan kız olgu. 2.Ulusal Cocuk Genetik Sempozyumu/ 22-24 Ekim 2015, Samsun (Ekim 2015) (Ekim 2015)
  • Emine İkbal Atlı, Hakan Gurkan, Selma Ulusal, Rıdvan Duran, Hilmi Tozkır. Ekstra derivatif kromozom 22 taşıyan bir olgu: Emanuel sendromu. 2.Ulusal Cocuk Genetik Sempozyumu/ 22-24 Ekim 2015, Samsun, (Ekim 2015) (Ekim 2015)
  • Selma Ulusal, Hakan Gürkan, Beril Varnatopu, Damla Eker, Hilmi Tozkır, Emine İkbal Atlı, Havva Nur Kendirci. De novo r(21) Saptanan Bir Olgu. (Eylül 2014) (Eylül 2014)
  • Atlı E.İ.,Akın A., Yakıcıer C.,XIII. Ulusal Tıbbi Biyoloji ve Genetik Kongresi Kuşadası, Akciğer Adenokarsinomlarında ALK Geni Yeniden Düzenlenmeleri (Ekim 2013)
  • Cantürk M., Çilingir O., Özdemir M., Emre R., Aldemir Ö., Durak B., Çiçek İ., Önür, H., Artan S., VIII. Ulusal Tıbbi Genetik Kongresi 2008, Subtelomerik FISH yöntemiyle saptanan kriptik 14q delesyonu ve 19p duplikasyonlu olgu (Mayıs 2008)
  • Artan S., Uludağ A.,Şener T.,Durak B.,Çilingir O.,Çiçek E.İ.,Yurdakul H.,Kurtçu K.,VII. Ulusal Prenatal Tanı ve Tıbbi Genetik Kongresi ,Prenatal Tanıda Saptanan t(10;12)(q22;q22) Vakası:Olgu Sunumu (Mayıs 2006)

Üye Olunan Kurum ve Kuruluşlar

  • Turkish medical genetics association
  • The European Society of Human Genetics
  • TUBİTAK/ARBİS
  • European Cytogenetics Association

Editörlük / Yayınlama

  • Advances in Oncology Research and Treatments (Mart 2016)

Yapılan Hakemlikler

  • MicroRNA-195 inhibits the proliferation and invasion of pancreatic cancer cells by targeting the fatty acid synthase/Wnt signaling pathway (Mayıs 2017)
  • Cause-Specific Mortality in Childhood Acute Lymphoblastic Leukemia at a Single Center in Iran (Nisan 2017)
  • A CASE REPORT OF POEMS SYNDROME: A DIAGNOSTIC CHALLENGE (Nisan 2017)
  • Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio help identify patients with non-small cell lung cancer and predict TNM stages (Mart 2017)
  • LDR GYNECOLOGICAL BRACHYTHERAPY BY Cs-137: DOSIMETRIC COMPARISON OF MACHESTER SYSTEM AND ICRU-38 (Şubat 2017)
  • Role of Human PAPILLOMA Virus infection in Cancer Cervix: Review article (Ocak 2017)
  • Metastatic Ewings Sarcoma: Revisiting the "Evidence on the Fence' (Ocak 2017)
  • Relaxation and Guided Imagery for Parents of Offspring with Developmental Disabilities (Ocak 2017)
  • Occurrence of Metachronous Multiple Malignancies. Review of the literature. Case of three Patients (Nisan 2016)
  • Molecular characterization of mecA and SCCmec genes in pathogenic Staphylococcus spp. collected from hospitals in Taif region, KSA (Mart 2016)

Ödüller

  • INTERPRETATION OF CYTOGENETIC/FISH RESULTS İN MULTIPLE MYELOMA (Şubat 2018)
  • Tekrarlayan gebelik kayıplarının kromozomal olarak ve trombofili gen mutasyonları açısından değerlendirilmesi (Şubat 2016)

» Verdiği Dersler

kromozomal hastalıklar

Tıbbi Biyoloji Ve Genetik